Histomorphological differentiation of non-erosive reflux disease and functional heartburn in patients with PPI-refractory heartburn
نویسندگان
چکیده
منابع مشابه
Functional heartburn and non-erosive reflux disease.
Gastroesophageal reflux disease (GERD) is a common disorder in Western countries. For many years our attention has been focused on patients with erosive esophagitis, but in recent times we have realized that endoscopy-negative reflux disease is the most common presentation of this illness, affecting up to 70% of these individuals. Patients with the non-erosive form (NERD) are a heterogeneous gr...
متن کاملFunctional heartburn has more in common with functional dyspepsia than with non-erosive reflux disease
INTRODUCTION Functional dyspepsia and non-erosive reflux disease (NERD) are prevalent gastrointestinal conditions with accumulating evidence regarding an overlap between the two. Still, patients with NERD represent a very heterogeneous group and limited data on dyspeptic symptoms in various subgroups of NERD are available. AIM To evaluate the prevalence of dyspeptic symptoms in patients with ...
متن کاملDistinction between patients with non-erosive reflux disease and functional heartburn
Non-erosive reflux disease (NERD) and functional heartburn (FH) are two different clinical entities and the clear distinction between the two forms is actually possible thanks to the use of impedance-pH monitoring. NERD is the more common manifestation of gastro-esophageal reflux disease (GERD), one of the most widespread chronic gastrointestinal disorders in Western countries. The absence of v...
متن کاملResponsiveness of measures of heartburn improvement in non-erosive reflux disease
BACKGROUND When measuring treatment effect on symptoms, the treatment success variable should be as responsive as possible. The aim of the study was to investigate the responsiveness of various treatment success variables in patients with symptoms of heartburn. METHODS A total of 1640 patients with non-erosive reflux disease (NERD) were treated with proton pump inhibitors for 4 weeks. Treatme...
متن کاملAmbulatory 24-hour multichannel intraluminal impedance-pH monitoring and high resolution endoscopy distinguish patients with non-erosive reflux disease from those with functional heartburn
AIMS To assess the contribution of 24-h esophageal multichannel intraluminal impedance and pH (MII-pH) monitoring and high resolution endoscopy (HRE) with i-scan imaging in differentiating non erosive reflux disease (NERD) from functional heartburn (FH). METHODS This is a retrospective cohort study of patients with heartburn from the Endoscopy Unit. NERD patients and FH patients were defined ...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology & Therapeutics
سال: 2013
ISSN: 0269-2813
DOI: 10.1111/apt.12428